Dermaroller Studies


Collagen Induction Therapy

“Percutaneous Collagen Induction” (PCI) or “Collagen Induction Therapy” (CIT) is a skin treatment in which the outer layers of the skin, epidermis and dermis, are punctured in a minimally invasive manner, activating the body's own repair process and the renewal of damaged skin tissue by increasing collagen production.​

With the CIT, the wound healing mechanisms are activated without damaging the epidermis; the puncture channels close again quickly.

Percutaneous collagen induction therapy:
an alternative treatment for scars, wrinkles and skin laxity

Authors
Aust, Matthias C. M.D.; Fernandes, Des M.D.; Kolokythas, Perikles M.D.; Kaplan, Hilton M. M.D.; Vogt, Peter M. M.D.​

Researchinstitute
Clinic for Plastic Surgery, Hand- and Reconstructive Surgery, Medical University Hannover​

Source
Plastic and Reconstructive Surgery, 2008, Vol.121(4), pp.1421-1429​

Summary
Extensive retrospective analysis, pioneering summary on micro-needling, but with non-equivalent micro-needling device.

Link to study

Microneedling Therapy in Atrophic Facial Scars: An Objective Assessment

Author
Imran Majid​

Researchinstitute
Cutis Skin- and Laser-Clinic, Govt Medical College, Srinagar, India​

Source
Journal of Cutaneous and Aesthetic Surgery, 2009, Vol.2(1), p.26-30​

Summary
Atrophic facial scars of grade 2 and 3 are reduced significantly; method is simple, safe and free of adverse effects. Device: MF8 

Link to study

Skin Cell Proliferation Stimulated by Microneedles

Authors
Horst Liebl, Luther C. Kloth

Researchinstitute
Department of Physical Therapy, Marquette University, P.O. Box 1881, Milwaukee, WI 53201-1881, USA​

Source
Journal of the American College of Clinical Wound Specialists, March 2012, Vol.4(1), pp.2-6​

Summary
Hypothesis on underlying mode of action; postulated role of MMPs confirmed by new result (El-Sheimy et al 2015).

Link to study

A prospective controlled assessment of Microneedling with the Dermaroller-device

Author
Schwarz M, H Laaff ​

Source
Plast Reconstr Surg 127(6):146e-148e. ​

Summary
Outcome was measured in terms of elastin content and thickness of epidermis All treated subjects reported an improvement in hyperchromia, smoothness and skin texture. The procedure was very well tolerated. Device: MF8

Link to study